3-pyridinecarbonitrile, 5-formyl-

3-pyridinecarbonitrile, 5-formyl- - Names and Identifiers

Name	5-formylpyridine-3-carbonitrile
Synonyms	LogP 5-Formylnicotinonitrile 3-Cyano-5-formylpyridine 5-ForMyl-nicotinonitrile 5-formylpyridine-3-carbonitril 5-FORNYL-3-PYRIDINECARBONITRILE 5-Fornyl-3-pyridinecarbonitrile 5-formylpyridine-3-carbonitrile 5-FORMYL-3-PYRIDINECARBONITRILE 5-Cyanopyridine-3-carboxaldehyde 3-pyridinecarbonitrile, 5-formyl- 3-Pyridinecarbonitrile, 5-formyl-
CAS	70416-53-4
InChI	InChI=1/C7H4N2O/c8-2-6-1-7(5-10)4-9-3-6/h1,3-5H

3-pyridinecarbonitrile, 5-formyl- - Physico-chemical Properties

Molecular Formula	C7H4N2O
Molar Mass	132.12
Density	1.24±0.1 g/cm3(Predicted)
Boling Point	229.3±20.0 °C(Predicted)
Flash Point	92.503°C
Vapor Presure	0.07mmHg at 25°C
pKa	-0.01±0.20(Predicted)
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.554

3-pyridinecarbonitrile, 5-formyl- - Introduction

It is an organic compound with the formula C8H5N3O. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: White to light yellow crystal powder.
-Solubility: Soluble in some organic solvents such as ethanol, ether and DMSO, slightly soluble in water.
-Melting point: about 100-103°C.
-Stability: Stable at room temperature.

Use:
-Intermediate in chemical reactions: It can be used as an important intermediate in organic synthesis and participates in many important chemical reactions, such as oxidation, reduction, and carbonylation.
-Drug synthesis: It can be used to synthesize drugs, pesticides and other organic compounds.

Preparation Method:
There are many preparation methods, and common methods include the following:
-Acylation reaction: by acylation reaction of 3-picolinonitrile, usually using formyl chloride or acid anhydride as acylating reagent, the reaction is carried out under alkali catalysis.
-Oxidation-reduction reaction on the pyridine ring: Oxidation of 3-pyridinecarbonitrile to 3-carboxy pyridine, and then reduction reaction to obtain pyridine.

Safety Information:
-no obvious toxicity to human body under normal use conditions.
-It is a chemical and should follow general laboratory safety practices to avoid contact with skin, eyes and inhalation.
-Keep sealed during storage and place in a cool, dry place.

Last Update：2024-04-09 02:00:47